Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Razadyne, Reminyl, Nivalin
Galantamine is a reversible, competitive acetylcholinesterase inhibitor used primarily to treat the cognitive decline associated with mild to moderate Alzheimer's disease and other forms of dementia. It works by increasing the levels of acetylcholine, a neurotransmitter essential for learning and memory, in the brain. Galantamine belongs to the class of cholinesterase inhibitors and is available in various forms, including immediate-release and extended-release tablets, oral solution, and transdermal patches.
For the treatment of mild to moderate Alzheimer's disease and vascular dementia.
Outcome:
Increased risk of galantamine side effects
Mechanism:
Ketoconazole inhibits CYP3A4, which metabolizes galantamine.
Outcome:
Slightly increased galantamine levels
Mechanism:
Cimetidine inhibits CYP2D6 and CYP3A4.
Outcome:
May slightly reduce galantamine absorption
Mechanism:
Altered gastric pH.
Most likely new formulation: Transdermal patch with improved bioavailability (2025, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood that galantamine will maintain its current regulatory status for the next 5 years.
Cholinesterase Inhibitor, Acetylcholinesterase Inhibitor
Tertiary alkaloid