Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Magnevist, Magnegita
Gadopentetate dimeglumine is a gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to enhance the visibility of internal organs, blood vessels, and other tissues. It belongs to the class of linear, ionic, gadolinium-based contrast agents (GBCAs). It works by shortening the T1 relaxation time of water protons in the body, leading to a brighter signal in T1-weighted MRI images, improving the differentiation between normal and abnormal tissues.
Used as a contrast agent in magnetic resonance imaging (MRI) to visualize internal organs, blood vessels, and other tissues.
Outcome:
Increased risk of nephrogenic systemic fibrosis (NSF)
Mechanism:
Additive renal toxicity
Outcome:
Reduced efficacy of Gd-DTPA
Mechanism:
Binding interaction
Outcome:
Slightly reduced absorption of Gd-DTPA
Mechanism:
Chelation
Most likely new formulation: targeted Gd-DTPA conjugates for specific disease imaging (2025, 70% confidence).
Based on usage patterns and safety profile, Gd-DTPA is likely to maintain its approved status for MRI contrast enhancement (95% confidence).
Contrast Agent, Gadolinium-based
Gadolinium Chelate