Medicines
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Discover all available medicines and treatments
Brand: Panhematin
Hemin is a porphyrin compound containing ferric iron (Fe3+) that is used to treat acute attacks of porphyria. Porphyrias are a group of rare, inherited, or acquired metabolic disorders affecting the production of heme, a crucial component of hemoglobin, myoglobin, and various enzymes. Hemin acts by reducing the overproduction of porphyrin precursors in the liver, thus alleviating the symptoms of acute porphyria attacks.
Treatment of acute porphyria attacks.
Outcome:
May exacerbate porphyria symptoms.
Mechanism:
Alcohol can induce heme synthesis, potentially worsening the underlying metabolic defect.
Outcome:
May not be beneficial and could potentially worsen iron overload in certain types of porphyria.
Mechanism:
Hemin already provides a source of iron, and additional supplementation may not be necessary or beneficial.
Outcome:
May delay absorption.
Mechanism:
Food can affect drug absorption kinetics.
Most likely new formulation: Extended-release hemin formulation (Year: 2026, 60% confidence)
Based on current usage patterns and clinical trial data, there is a low (less than 5%) likelihood of major regulatory changes for hemin in the next 5 years.
Porphyria Treatment, Hematinic Agent
Porphyrin