Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Hexalen
Hexamethylmelamine, also known by its generic name altretamine, is an antineoplastic agent primarily used in the treatment of ovarian cancer. It's classified as an alkylating agent, although its precise mechanism of action is not fully understood. It is believed to be metabolized to active metabolites that disrupt DNA and RNA synthesis, leading to cell death. Hexamethylmelamine is typically used in combination with other chemotherapy drugs.
Used in combination with other chemotherapy drugs to treat ovarian cancer.
Outcome:
Increased risk of neurotoxicity
Mechanism:
Possible synergistic neurotoxic effects
Outcome:
Increased risk of nausea and vomiting
Mechanism:
Additive gastrointestinal effects
Outcome:
Reduced absorption of hexamethylmelamine
Mechanism:
Altered drug absorption
Most likely new formulation: Liposomal encapsulation for improved delivery (2026, 30% confidence)
Based on current usage trends and ongoing research, there is a low likelihood of significant regulatory changes in the next 5 years.
Antineoplastic, Alkylating Agent
Triazine