Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Isopto Homatropine, Ak-Homatropine
Homatropine is an anticholinergic medication primarily used to dilate the pupils (mydriasis) and paralyze accommodation (cycloplegia) during eye examinations. It belongs to the class of muscarinic antagonists and acts by blocking the action of acetylcholine, a neurotransmitter, at muscarinic receptors in the eye. This allows for easier examination of the internal structures of the eye. Homatropine is also occasionally used to treat certain types of gastrointestinal disorders and to reduce excessive sweating.
Used for pupil dilation during eye exams, treatment of certain gastrointestinal disorders, and reduction of excessive sweating.
Outcome:
Increased anticholinergic effects (e.g., dry mouth, blurred vision, constipation)
Mechanism:
Additive anticholinergic activity
Outcome:
Reduced gastrointestinal motility
Mechanism:
Additive effects on gastrointestinal motility
Outcome:
Delayed absorption
Mechanism:
Delayed gastric emptying
Most likely new formulation: extended-release ophthalmic insert for sustained mydriasis (Year: 2026, 70% confidence)
Based on current usage trends and safety profile, homatropine is likely to maintain its current FDA approval status for ophthalmic use.
Anticholinergic, Antimuscarinic
Tropane Alkaloid