Medicines
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Discover all available medicines and treatments
Brand: Extraneal, Nutrineal PD4
Icodextrin is a glucose polymer used as an osmotic agent in peritoneal dialysis solutions. It is a colloid osmotic agent that helps to remove excess fluid from the body during peritoneal dialysis. Unlike glucose-based solutions, icodextrin is absorbed more slowly from the peritoneal cavity, allowing for longer dwell times and potentially improved fluid removal, especially in patients with ultrafiltration failure.
Used in peritoneal dialysis for patients with ultrafiltration failure.
Outcome:
Increased risk of ototoxicity
Mechanism:
Additive effects on renal function
Outcome:
Altered electrolyte balance
Mechanism:
Interaction with phosphate absorption
Outcome:
Altered absorption of certain medications
Mechanism:
Changes in stomach pH
Most likely new formulation: Improved icodextrin solutions with enhanced biocompatibility (Year: 2025, 70% confidence)
Based on current usage trends and clinical trial data, icodextrin is likely to maintain its current regulatory status for peritoneal dialysis.
Osmotic Agent
Glucose Polymer