Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Herplex, Dendrid, Stoxil
Idoxuridine is an antiviral medication primarily used for the topical treatment of herpes simplex keratitis, a viral infection affecting the cornea. It is a pyrimidine nucleoside analogue that inhibits viral DNA synthesis, thereby halting viral replication. Idoxuridine belongs to the class of antimetabolites.
For the topical treatment of herpes simplex keratitis.
Outcome:
Increased ocular toxicity
Mechanism:
Additive toxicity
Outcome:
Prolonged exposure to idoxuridine
Mechanism:
Decreased tear production
Outcome:
Dilution of drug concentration
Mechanism:
Physical dilution
Most likely new formulation: sustained-release ophthalmic insert (Year 2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant regulatory changes in the next 5 years.
Antiviral, Antimetabolite
Pyrimidine Nucleoside Analogue