Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Natrilix, Lozol, Fludex, Indapamid, Ipamid, Termion
Indapamide is a thiazide-like diuretic primarily used to treat hypertension (high blood pressure). It works by increasing the excretion of sodium and chloride in the urine, which helps lower blood pressure. It also has vasodilatory effects, further contributing to blood pressure reduction. While structurally similar to thiazide diuretics, indapamide exhibits distinct pharmacological properties.
For treating hypertension (high blood pressure).
Outcome:
Increased lithium levels and toxicity
Mechanism:
Reduced lithium clearance
Outcome:
Additive hypotensive effect
Mechanism:
Vasodilation
Outcome:
Reduced absorption of indapamide
Mechanism:
Changes in gastric pH
Most likely new formulation: extended-release combination with other antihypertensives (2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low ( <5%) likelihood of any major regulatory changes in the next 5 years.
Thiazide-like Diuretic, Antihypertensive
Indoline Sulfonamide