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Brand: Isovue, Niopam, Iopamiron
Iopamidol is a non-ionic, water-soluble radiographic contrast medium used in various imaging procedures. It belongs to a class of compounds known as iodinated contrast media. These agents enhance the visibility of internal structures during X-ray examinations by absorbing X-rays more effectively than surrounding tissues. Iopamidol's non-ionic nature contributes to its relatively low osmolality, which is associated with fewer adverse reactions compared to older, ionic contrast agents.
Used for enhancing visualization of internal structures during X-ray procedures including angiography, urography, and CT scans.
Outcome:
Lactic acidosis
Mechanism:
Reduced renal clearance of metformin
Outcome:
Reduced efficacy of beta-blockers in treating adverse reactions
Mechanism:
Unknown
Outcome:
Dehydration
Mechanism:
Diuretic effect of alcohol
Most likely new formulation: Improved formulations with reduced viscosity and osmolality (Year: 2026, 70% confidence).
Based on current usage and safety profiles, iopamidol is expected to remain a widely used contrast agent, with a 90% likelihood of continued approval for the next 5 years.
Radiographic Contrast Agent, Iodinated Contrast Medium
Non-ionic, water-soluble, triiodinated benzene derivative