Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: DynaCirc, Lomir, Prescal
Isradipine is a calcium channel blocker primarily used to treat high blood pressure (hypertension). It belongs to the dihydropyridine class of calcium channel blockers and works by relaxing blood vessels, allowing blood to flow more easily. Isradipine can also be used to treat angina pectoris (chest pain) by improving blood flow to the heart.
Used to treat high blood pressure and angina pectoris.
Outcome:
Increased isradipine levels and risk of side effects.
Mechanism:
Inhibition of CYP3A4 metabolism.
Outcome:
Increased risk of bradycardia.
Mechanism:
Additive effects on heart rate.
Outcome:
May slightly reduce the antihypertensive effect of isradipine.
Mechanism:
Caffeine can stimulate the cardiovascular system.
Most likely new formulation: Extended-release formulation for once-daily dosing (Year: 2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low probability ( <5%) of any major regulatory changes in the next 2 years.
Calcium Channel Blocker, Antihypertensive, Antianginal
Dihydropyridine