Medicines
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Brand: Dyrenium, Dytac, Maxzide, Triamterene HCTZ
Triamterene, sold under the brand name Dyrenium among others, is a potassium-sparing diuretic often used in combination with thiazide diuretics for the treatment of high blood pressure or swelling caused by fluid accumulation. It acts by blocking a sodium channel in the distal tubule of the kidney, thus reducing sodium reabsorption and increasing water excretion while conserving potassium. It belongs to the class of pteridine diuretics.
Used to treat fluid retention (edema) and high blood pressure (hypertension).
Most likely new formulation: Combination therapy with other antihypertensives (2024, 70% confidence)
Based on current usage trends and patent expirations, generic triamterene formulations are expected to maintain a stable market share.
Potassium-sparing diuretic
Pteridine