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Brand: Fosrenol
Lanthanum carbonate is a phosphate binder used to reduce phosphate levels in the blood of people with end-stage renal disease (ESRD) who are on dialysis. It works by binding to phosphate in the gut, preventing its absorption into the bloodstream. It belongs to the class of drugs known as phosphate binders and is administered orally.
Reduces phosphate levels in patients with end-stage renal disease (ESRD) on dialysis.
Outcome:
Reduced effectiveness of lanthanum carbonate
Mechanism:
Competition for phosphate binding in the gut
Outcome:
Reduced absorption of ketoconazole
Mechanism:
Possible binding interaction
Outcome:
May slightly decrease lanthanum absorption
Mechanism:
Unknown
Most likely new formulation: Chewable tablets for easier administration (Year: 2026, 60% confidence)
Based on current usage and clinical trial data, there is a low likelihood of significant regulatory changes in the near future.
Phosphate Binder
Lanthanide