Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Generic: Lasofoxifene
Lasofoxifene is a selective estrogen receptor modulator (SERM) primarily used for the treatment and prevention of osteoporosis in postmenopausal women. It acts as an estrogen agonist in bone tissue, promoting bone formation and reducing bone resorption, thus increasing bone mineral density. Lasofoxifene exhibits estrogen antagonist activity in breast and uterine tissues, mitigating the risk of estrogen-related cancers in these areas.
For treatment and prevention of osteoporosis in postmenopausal women.
Outcome:
Decreased effectiveness of lasofoxifene
Mechanism:
Competition for estrogen receptors
Outcome:
No clinically significant interaction expected
Mechanism:
Different metabolic pathways
Outcome:
May slightly reduce lasofoxifene absorption
Mechanism:
Changes in stomach pH
Most likely new formulation: Extended-release formulation (Year: 2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant regulatory changes in the next 5 years.
Selective Estrogen Receptor Modulator (SERM)
Benzothiophene derivative