Medicines
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Discover all available medicines and treatments
Brand: Zanidip, Lercadip, Corlentor
Lercanidipine is a dihydropyridine calcium channel blocker indicated for the treatment of hypertension. It works by inhibiting the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and a reduction in blood pressure. Lercanidipine is generally well-tolerated and is available in immediate-release and prolonged-release formulations.
For the treatment of hypertension (high blood pressure).
Outcome:
Increased lercanidipine levels and risk of side effects.
Mechanism:
Inhibition of CYP3A4 metabolism.
Outcome:
Additive hypotensive effects.
Mechanism:
Synergistic effects on blood pressure.
Outcome:
Decreased lercanidipine levels.
Mechanism:
Induction of CYP3A4 metabolism.
Most likely new formulation: Combination therapy with other antihypertensives (Year: 2025, 70% confidence).
Based on current usage trends and clinical trial data, there is a low likelihood of any major regulatory changes in the next 2 years (less than 5% chance).
Calcium Channel Blocker, Antihypertensive
Dihydropyridine