Medicines
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Discover all available medicines and treatments
Brand: Keppra, Keppra XR, Spritam, Desitrend
Levetiracetam is an anticonvulsant medication used to treat various types of seizures in adults and children. It belongs to the pyrrolidone derivative class of antiepileptic drugs and is believed to work by modulating synaptic vesicle protein 2A (SV2A) activity, thereby reducing neuronal excitability. Levetiracetam is available as both immediate-release and extended-release formulations.
Used to treat various types of seizures in adults and children, including partial-onset, myoclonic, and tonic-clonic seizures.
Suicidal thoughts and behavior.
Outcome:
Decreased levetiracetam levels
Mechanism:
Induction of CYP3A4 enzymes
Outcome:
Increased risk of levetiracetam toxicity
Mechanism:
Reduced clearance
Outcome:
Slightly decreased absorption
Mechanism:
Delayed gastric emptying
Most likely new formulation: extended-release formulations with improved tolerability (2025, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood of levetiracetam remaining a first-line treatment for partial-onset seizures for the next 5 years.
Anticonvulsant, Antiepileptic
Pyrrolidone Derivative