Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Betagan, Akbeta, Vistagan
Levobunolol is a non-selective beta-adrenergic receptor antagonist used primarily to treat glaucoma. It reduces intraocular pressure by decreasing the production of aqueous humor. It belongs to the class of drugs known as beta-blockers.
Used to treat glaucoma and ocular hypertension.
Outcome:
Increased risk of bradycardia, hypotension, and heart block.
Mechanism:
Additive beta-blocking effects.
Outcome:
Reduced antihypertensive effect of levobunolol.
Mechanism:
NSAIDs can inhibit prostaglandin synthesis, which can affect blood pressure regulation.
Outcome:
Reduced absorption of levobunolol.
Mechanism:
Altered gastrointestinal pH.
Most likely new formulation: Sustained-release implant (Year: 2028, 30% confidence)
Based on current usage trends and clinical trial data, there is a low (<5%) likelihood of any major regulatory changes for levobunolol in the next 5 years.
Beta-adrenergic blocking agent, Antiglaucoma agent
Aryloxypropanolamine