Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Vyvanse
Lisdexamfetamine is a central nervous system stimulant used to treat attention-deficit/hyperactivity disorder (ADHD) and moderate to severe binge eating disorder (BED). It is a prodrug of dextroamphetamine, meaning it is inactive until it is metabolized in the body. It belongs to the substituted amphetamine class of medications.
For the treatment of attention-deficit/hyperactivity disorder (ADHD) and moderate to severe binge eating disorder (BED).
Potential for abuse and dependence. Sudden death has been reported in association with CNS stimulants at usual doses in children and adolescents with structural cardiac abnormalities or other serious heart problems.
Outcome:
Hypertensive crisis
Mechanism:
Increased release of norepinephrine and dopamine.
Outcome:
Increased lisdexamfetamine absorption
Mechanism:
Altered gastric pH.
Outcome:
Additive stimulant effects
Mechanism:
Similar mechanisms of action.
Most likely new formulation: extended-release capsules for improved once-daily dosing (2025, 80% confidence)
Based on increasing prescriptions and positive clinical trial data, there is a 70% likelihood of expanded indications for lisdexamfetamine within the next 5 years.
Central Nervous System Stimulant
Substituted Amphetamine