Medicines
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Discover all available medicines and treatments
Brand: Skytrofa
Lonapegsomatropin is a long-acting recombinant human growth hormone (rhGH) analog. It is a prodrug that is converted to somatropin after subcutaneous administration. Somatropin stimulates growth and cell reproduction in humans and other animals. It is used to treat growth failure in children and adults with growth hormone deficiency (GHD).
Lonapegsomatropin is used to treat growth failure in children and adults with growth hormone deficiency.
Outcome:
May increase the risk of hypoglycemia
Mechanism:
Increased insulin sensitivity
Outcome:
May affect growth hormone levels
Mechanism:
Unknown
Outcome:
May decrease absorption
Mechanism:
Changes in stomach pH
Most likely new formulation: Sustained-release formulation (2025, 70% confidence)
Based on clinical trial data and post-market surveillance, lonapegsomatropin has a high likelihood of remaining a valuable treatment option for GHD.
Growth Hormone
Protein