Medicines
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Discover all available medicines and treatments
Brand: Noctamid, Loramet, Minias, Ergocalm, Sedatival
Lormetazepam is a short-acting benzodiazepine used for the short-term treatment of insomnia, especially difficulty falling asleep. It belongs to the benzodiazepine class and works by enhancing the effect of the inhibitory neurotransmitter GABA in the central nervous system, leading to sedative, hypnotic, anxiolytic, and muscle-relaxant effects.
For short-term treatment of insomnia, especially difficulty falling asleep.
Outcome:
Increased sedation, respiratory depression
Mechanism:
Additive CNS depressant effects
Outcome:
Increased lormetazepam levels
Mechanism:
Displacement from plasma protein binding sites
Outcome:
Delayed absorption
Mechanism:
Altered gastric emptying
Most likely new formulation: Extended-release formulation for improved sleep maintenance (Year: 2028, 30% confidence)
Based on current usage trends and the availability of alternative treatments, there is a low probability (<5%) of lormetazepam being approved by the FDA in the next 5 years.
Benzodiazepine, Hypnotic, Anxiolytic
Benzodiazepine