Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Lotemax, Alrex, Loteflam
Loteprednol etabonate is a corticosteroid medication primarily used to treat inflammatory and allergic conditions of the eye. It belongs to the class of corticosteroids, which are synthetic analogs of hormones produced by the adrenal glands. Loteprednol works by suppressing the immune system and reducing inflammation in the eye. It is available in various ophthalmic formulations, including drops, ointment, and gel.
For treating inflammatory and allergic conditions of the eye, such as allergic conjunctivitis, uveitis, and postoperative inflammation.
Outcome:
Increased loteprednol levels
Mechanism:
Ritonavir inhibits CYP3A4, which metabolizes loteprednol.
Outcome:
Increased risk of gastrointestinal bleeding
Mechanism:
Additive effects on gastric mucosa.
Outcome:
Reduced loteprednol absorption
Mechanism:
Changes in gastric pH.
Most likely new formulation: sustained-release intravitreal implant for the treatment of macular edema (Year 2026, 60% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of loteprednol maintaining its current FDA approval status for ophthalmic use over the next 5 years.
Corticosteroid, Ophthalmic Agent
Corticosteroid Ester