Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Mevacor, Altoprev, Altocor
Lovastatin is a lipid-lowering agent belonging to the statin class. It works by inhibiting HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. This leads to reduced cholesterol production in the liver, lowering total cholesterol and LDL cholesterol levels in the blood. Lovastatin is commonly used to prevent cardiovascular disease in individuals at high risk.
Used to lower cholesterol and reduce the risk of cardiovascular disease.
Outcome:
Increased risk of myopathy and rhabdomyolysis
Mechanism:
Inhibition of lovastatin metabolism
Outcome:
Decreased lovastatin absorption
Mechanism:
Binding to lovastatin in the gut
Outcome:
Decreased lovastatin absorption
Mechanism:
Binding to lovastatin in the gut
Most likely new formulation: Combination therapy with other lipid-lowering agents (2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of any major regulatory changes in the near future.
HMG-CoA Reductase Inhibitor, Statin
Statin