Medicines
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Discover all available medicines and treatments
Brand: Sulfamylon
Mafenide acetate is a topical antibacterial agent used to treat and prevent infections in burn wounds. It's a sulfonamide antibiotic that works by inhibiting bacterial growth. It penetrates eschar, which is crucial for its effectiveness in burn treatment.
For the treatment and prevention of infections in second- and third-degree burns.
Outcome:
Increased risk of bleeding
Mechanism:
Mafenide can displace warfarin from plasma proteins
Outcome:
Increased risk of methemoglobinemia
Mechanism:
Additive effects on methemoglobin formation
Outcome:
Potential antagonism
Mechanism:
Different mechanisms of action
Most likely new formulation: sustained-release mafenide cream (Year: 2026, 70% confidence)
Based on current usage and safety profile, mafenide is expected to remain a valuable treatment option for burn infections (90% confidence).
Sulfonamide Antibiotic, Topical Antibacterial
Sulfonamide