Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Meclomen, Lysalgo
Meclofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It belongs to the fenamate class of NSAIDs and works by inhibiting cyclooxygenase (COX), an enzyme responsible for producing prostaglandins, which mediate pain and inflammation. It is available in both oral and topical formulations.
For the treatment of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and other musculoskeletal conditions.
Outcome:
Increased bleeding risk
Mechanism:
Meclofenamate can displace warfarin from protein binding sites, increasing its free concentration.
Outcome:
Reduced antihypertensive effect
Mechanism:
NSAIDs can blunt the vasodilatory effects of ACE inhibitors.
Outcome:
Reduced absorption of meclofenamate
Mechanism:
Antacids can alter gastric pH and affect drug absorption.
Most likely new formulation: Topical extended-release patch (Year: 2026, 60% confidence)
Based on current usage trends and safety profile, there is a low ( <5%) likelihood of regulatory changes in the next 5 years.
Nonsteroidal Anti-inflammatory Drug (NSAID), Fenamate
Fenamate