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Brand: Carbocaine, Polocaine, Scandonest, Isocaine
Mepivacaine is a local anesthetic of the amide type used to numb tissue in a specific area. It is commonly used in dentistry, for nerve blocks during surgery, and for minor surgical procedures. Mepivacaine works by blocking sodium channels, preventing nerve signals from reaching the brain and thus eliminating the sensation of pain in the targeted area. It is considered an intermediate-acting local anesthetic.
Used for local anesthesia in dentistry, surgery, and minor procedures.
Outcome:
Increased risk of severe hypotension
Mechanism:
Additive hypotensive effects
Outcome:
Increased sedation
Mechanism:
Additive CNS depressant effects
Outcome:
May decrease the effectiveness of mepivacaine
Mechanism:
Antagonistic effects on CNS
Most likely new formulation: Extended-release mepivacaine for postoperative pain management (2025, 70% confidence).
Based on current usage trends and safety profile, mepivacaine is expected to maintain its approved status with no major regulatory changes in the near future (95% confidence).
Local Anesthetic, Amide
Amide