Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Equanil, Miltown, Meprospan, Meprotabs
Meprobamate is a carbamate derivative with anxiolytic and sedative-hypnotic properties. It acts as a central nervous system depressant, affecting several neurotransmitter systems, including GABA, glutamate, and serotonin. Historically used as an anxiolytic and muscle relaxant, its use has declined significantly due to concerns about dependence, abuse, and interactions with other drugs.
For the short-term relief of anxiety and muscle spasms.
Outcome:
Increased sedation, respiratory depression
Mechanism:
Additive CNS depression
Outcome:
Increased sedation
Mechanism:
Additive CNS depression
Outcome:
Reduced sedative effects
Mechanism:
Caffeine antagonism
Most likely new formulation: Extended-release formulation for improved adherence (Year: 2026, 15% confidence)
Due to the historical decline in usage and safety concerns, the likelihood of stricter regulatory measures regarding meprobamate usage in the next 5 years is estimated at 30%.
Anxiolytic, Sedative-Hypnotic, Carbamate Derivative
Carbamate