Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Mersyndol, Mersyndol Forte, Mersyndol with Codeine
Mersyndol is a combination medication containing paracetamol (an analgesic and antipyretic), codeine (an opioid analgesic), and doxylamine (an antihistamine with sedative properties). It is primarily used for the relief of moderate to severe pain, particularly when associated with headache, cold and flu symptoms, or menstrual cramps. The codeine component provides stronger pain relief than paracetamol alone, while doxylamine helps with sleep and reduces any associated anxiety or restlessness.
For the relief of moderate to severe pain, particularly headaches, cold and flu symptoms, and menstrual cramps.
Outcome:
Increased sedation and respiratory depression
Mechanism:
Additive CNS depressant effects
Outcome:
Increased drowsiness
Mechanism:
Additive sedative effects
Outcome:
Reduced paracetamol absorption
Mechanism:
Altered gastric pH
Most likely new formulation: Extended-release version (Year: 2025, 60% confidence)
Due to the opioid component, Mersyndol is unlikely to be approved for over-the-counter sale in most countries.
Analgesic, Opioid Combination
Paracetamol, Codeine, Doxylamine