Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Celontin
Methsuximide is an anticonvulsant medication primarily used to treat absence seizures, a type of generalized epilepsy. It belongs to the succinimide class of antiepileptic drugs and works by suppressing the abnormal electrical activity in the brain that causes seizures. Methsuximide is generally considered a second-line treatment option for absence seizures when other medications, such as ethosuximide, are ineffective or not tolerated.
Used to treat absence seizures.
Outcome:
Increased sedation and impaired coordination.
Mechanism:
Additive CNS depressant effects.
Outcome:
Potential for increased liver toxicity.
Mechanism:
Both drugs are metabolized by the liver.
Outcome:
Reduced absorption of methsuximide.
Mechanism:
Changes in gastric pH.
Most likely new formulation: Extended-release formulation (Year: 2026, 30% confidence)
Based on current usage trends and clinical trial activity, there is a low (<5%) likelihood of significant regulatory changes for methsuximide in the next 5 years.
Anticonvulsant, Antiepileptic
Succinimide