Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: OptiPranolol, Betanol, Disorat, Metipra
Metipranolol is a non-selective beta-adrenergic blocking agent used primarily to treat elevated intraocular pressure, particularly in open-angle glaucoma and ocular hypertension. It belongs to the class of beta blockers and works by decreasing the production of aqueous humor, the fluid that fills the front part of the eye. This helps to lower the pressure inside the eye, preventing damage to the optic nerve.
Used to treat elevated intraocular pressure in open-angle glaucoma and ocular hypertension.
Outcome:
Additive bradycardia, hypotension
Mechanism:
Synergistic effects on heart rate and blood pressure
Outcome:
Decreased antihypertensive effect
Mechanism:
NSAIDs can inhibit prostaglandin synthesis, which can reduce the effectiveness of beta-blockers
Outcome:
Reduced absorption of metipranolol
Mechanism:
Antacids can alter gastrointestinal pH, affecting absorption
Most likely new formulation: Sustained-release ocular insert (Year: 2026, 60% confidence)
Based on current usage trends and safety profile, there is a low probability (<5%) of regulatory changes impacting metipranolol's availability in the next 5 years.
Beta-blocker, Antiglaucoma Agent
Non-selective beta-adrenergic antagonist