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Discover all available medicines and treatments
Brand: Versed, Hypnovel, Dormicum
Midazolam is a short-acting benzodiazepine used for sedation, anesthesia, and to treat seizures. It works by enhancing the effect of GABA, a neurotransmitter that inhibits brain activity. Midazolam is available in various forms, including injection, tablet, and oral solution.
Used for sedation, anesthesia, and treatment of seizures.
Respiratory depression and arrest can occur with midazolam, especially with intravenous administration. Close monitoring and resuscitation equipment should be readily available.
Outcome:
Increased sedation and respiratory depression
Mechanism:
Additive CNS depressant effects
Outcome:
Increased midazolam levels
Mechanism:
Inhibition of CYP3A4 metabolism
Outcome:
Decreased midazolam levels
Mechanism:
Induction of CYP3A4 metabolism
Most likely new formulation: Intranasal spray for rapid seizure control (Year: 2026, 70% confidence)
Based on current usage trends and emerging alternatives, there is a 20% likelihood of stricter regulatory controls on midazolam prescriptions within the next 5 years.
Benzodiazepine
Imidazobenzodiazepine