Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Aurorix, Manerix, Moclamine
Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA) primarily used to treat depression and social anxiety disorder. It belongs to the class of antidepressants and works by increasing the levels of neurotransmitters like serotonin, norepinephrine, and dopamine in the brain. Unlike older, irreversible MAOIs, moclobemide has a more favorable safety profile and fewer dietary restrictions.
For the treatment of major depressive disorder and social anxiety disorder.
Outcome:
Hypertensive crisis
Mechanism:
Increased tyramine levels due to MAO-A inhibition
Outcome:
Increased moclobemide levels
Mechanism:
Inhibition of moclobemide metabolism
Outcome:
Potential alteration of anticoagulant effect
Mechanism:
May affect warfarin metabolism
Most likely new formulation: Extended-release formulation (2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low probability (<10%) of FDA approval for moclobemide in the next 5 years.
Antidepressant, RIMA
Benzamide