Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Provigil, Alertec, Modavigil, Modalert, Vigil, Sparlon
Modafinil is a wakefulness-promoting agent used to treat excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea/hypopnea syndrome (OSAHS), and shift work sleep disorder (SWSD). It is classified as a eugeroic, meaning it promotes wakefulness without the typical stimulant effects of amphetamines. Its exact mechanism of action is not fully understood but is thought to involve multiple neurotransmitter systems, including dopamine, norepinephrine, histamine, and orexin.
For treating excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder.
Outcome:
Increased bleeding risk
Mechanism:
Modafinil may inhibit CYP2C9, which metabolizes warfarin.
Outcome:
Additive sedative effects
Mechanism:
Alcohol has sedative properties.
Outcome:
No clinically significant interaction expected
Mechanism:
Unknown
Most likely new formulation: extended-release formulation for improved adherence (Year 2025, 70% confidence)
Based on current usage patterns and emerging research on long-term effects, there is a 15% likelihood of increased regulatory scrutiny regarding off-label prescribing within the next 5 years.
Wakefulness-promoting agent, Eugeroic
Benzhydryl Sulfinyl Acetamide