Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Physiotens, Moxon, Tensimin
Moxonidine is a centrally acting antihypertensive drug. It acts as an imidazoline receptor agonist, primarily targeting the I1-imidazoline receptors in the rostral ventrolateral medulla of the brainstem. This action reduces sympathetic nerve activity, leading to a decrease in peripheral vascular resistance and blood pressure. Moxonidine is also believed to have some affinity for alpha-2 adrenergic receptors, contributing to its antihypertensive effects. It is typically used in the treatment of mild to moderate hypertension.
For the treatment of mild to moderate hypertension.
Outcome:
Increased antihypertensive effect
Mechanism:
Additive hypotensive effects
Outcome:
Additive hypotensive effects
Mechanism:
Combined reduction in blood volume and peripheral resistance
Outcome:
Mild drowsiness
Mechanism:
Additive CNS effects
Most likely new formulation: Extended-release formulation (Year: 2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of FDA approval in the near future.
Antihypertensive, Imidazoline Receptor Agonist
Imidazoline