Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Corgard
Nadolol is a non-selective beta-blocker used to treat high blood pressure, angina (chest pain), and certain heart rhythm disorders. It works by blocking the effects of adrenaline on the heart and blood vessels, leading to a slower heart rate, reduced blood pressure, and decreased workload on the heart. It belongs to the class of drugs known as beta-adrenergic blocking agents.
For treating high blood pressure, angina (chest pain), and certain heart rhythm disorders.
Outcome:
Severe rebound hypertension
Mechanism:
Additive hypotensive effects and potential for unopposed alpha-adrenergic stimulation.
Outcome:
Decreased antihypertensive effect
Mechanism:
NSAIDs can reduce the effectiveness of beta-blockers by inhibiting prostaglandin synthesis.
Outcome:
Delayed absorption
Mechanism:
Food may delay the absorption of nadolol, but the extent of absorption is not significantly affected.
Most likely new formulation: Extended-release formulation for improved patient compliance (2025, 30% confidence)
Based on historical usage patterns and current clinical trials, there is a low probability (<5%) of nadolol being withdrawn from the market in the next 5 years.
Beta-blocker, Antihypertensive, Antianginal
Non-selective beta-blocker