Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Amerge, Naramig
Naratriptan is a selective serotonin 5-HT1B/1D receptor agonist used to treat migraine headaches. It belongs to the triptan class of drugs, which work by constricting blood vessels in the brain and reducing inflammation associated with migraine attacks. Naratriptan does not prevent migraines or reduce the number of attacks but is effective in relieving migraine symptoms once they have begun.
For the acute treatment of migraine with or without aura.
Outcome:
Prolonged vasospasm
Mechanism:
Additive vasoconstriction
Outcome:
Increased naratriptan levels
Mechanism:
Inhibition of naratriptan metabolism
Outcome:
Enhanced analgesic effect
Mechanism:
Additive effects
Most likely new formulation: A quick-dissolving oral film (2026, 70% confidence).
Based on current usage trends and clinical trial data, there is a low (5%) likelihood of any major regulatory changes for naratriptan in the next 5 years.
Triptan, Serotonin Receptor Agonist, Antimigraine Agent
Tryptamine Derivative