Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Bystolic, Nebilet, Nebivolol Hydrochloride
Nebivolol is a third-generation, cardioselective beta-1 receptor blocker used primarily to treat hypertension (high blood pressure). It also possesses some vasodilating properties, possibly through nitric oxide pathways, which contributes to its blood pressure-lowering effects. It is generally well-tolerated and is available in both immediate-release and controlled-release formulations.
For the treatment of hypertension (high blood pressure).
Outcome:
Increased risk of bradycardia
Mechanism:
Additive effects on heart rate reduction
Outcome:
Reduced nebivolol effectiveness
Mechanism:
Increased metabolism of nebivolol by rifampicin
Outcome:
Reduced nebivolol absorption
Mechanism:
Binding of nebivolol in the gut
Most likely new formulation: Combination therapy with other antihypertensives (Year: 2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low (5%) likelihood of any major regulatory changes to nebivolol's status in the next 5 years.
Beta-blocker, Antihypertensive
Aryloxypropanolamine