Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Nevanac, Ilevro
Nepafenac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used to treat pain and inflammation after cataract surgery. It is a prodrug of amfenac, which inhibits both cyclooxygenase (COX)-1 and COX-2 enzymes, thereby reducing prostaglandin production and mitigating inflammation.
For pain and inflammation following cataract surgery.
Outcome:
Increased bleeding risk
Mechanism:
Nepafenac can inhibit platelet function.
Outcome:
Increased lithium levels
Mechanism:
NSAIDs can reduce lithium clearance.
Outcome:
Reduced nepafenac absorption
Mechanism:
Altered gastric pH.
Most likely new formulation: sustained-release implant (Year: 2026, 60% confidence)
Based on usage trends and clinical trial data, there is a low likelihood of changes to nepafenac's regulatory status in the near future.
Nonsteroidal anti-inflammatory drug (NSAID)
Propionic Acid Derivative