Medicines
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Discover all available medicines and treatments
Brand: Natrecor
Nesiritide is a recombinant form of human B-type natriuretic peptide (BNP) used in the short-term treatment of acutely decompensated heart failure in patients who have dyspnea at rest or with minimal activity. It belongs to the class of drugs known as vasodilators and works by relaxing blood vessels, reducing the workload on the heart, and increasing the excretion of sodium and water.
For short-term treatment of acutely decompensated heart failure with dyspnea at rest or with minimal activity.
Outcome:
Hypotension
Mechanism:
Additive vasodilatory effects
Outcome:
Reduced effectiveness of nesiritide
Mechanism:
Inhibition of renal prostaglandin synthesis
Outcome:
Reduced absorption of nesiritide
Mechanism:
Chelation or altered pH
Most likely new formulation: Extended-release nesiritide (Year: 2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low probability of significant changes to nesiritide's regulatory status in the next 5 years.
Vasodilator, Human B-type Natriuretic Peptide
Recombinant human B-type natriuretic peptide