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Discover all available medicines and treatments
Brand: Cardene, Cardene SR, Loxen
Nicardipine is a calcium channel blocker primarily used to treat high blood pressure and angina (chest pain). It works by relaxing blood vessels, allowing blood to flow more easily and reducing the workload on the heart. It belongs to the dihydropyridine class of calcium channel blockers, known for their selective action on vascular smooth muscle.
For treating high blood pressure and angina (chest pain).
Outcome:
Increased nicardipine levels
Mechanism:
Inhibition of CYP3A4 metabolism
Outcome:
Increased risk of hypotension
Mechanism:
Additive effects on blood pressure
Outcome:
May slightly decrease the antihypertensive effect
Mechanism:
Mild vasoconstriction
Most likely new formulation: extended-release combination with other antihypertensives (Year: 2026, 70% confidence)
Based on current usage trends and clinical trial data, there is a low (5%) likelihood of any major regulatory changes in the next 2 years.
Calcium Channel Blocker, Antihypertensive, Antianginal
Dihydropyridine