Medicines
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Discover all available medicines and treatments
Brand: Sular, Syscor
Nisoldipine is a calcium channel blocker primarily used to treat high blood pressure (hypertension). It belongs to the dihydropyridine class of calcium channel blockers, which work by relaxing the muscles of the blood vessels, allowing them to widen and reducing blood pressure. It is generally well-tolerated but may cause side effects such as headache, dizziness, flushing, and peripheral edema.
Used to treat high blood pressure (hypertension).
Outcome:
Increased nisoldipine levels
Mechanism:
Inhibition of CYP3A4 metabolism
Outcome:
Additive hypotensive effects
Mechanism:
Both alcohol and nisoldipine can lower blood pressure
Outcome:
Potential decrease in nisoldipine absorption
Mechanism:
Changes in stomach pH
Most likely new formulation: extended-release formulation for improved patient compliance (Year: 2025, 65% confidence).
Based on current usage trends and patent expiry, generic versions of nisoldipine are likely to maintain a significant market share (70% probability).
Calcium Channel Blocker, Dihydropyridine
Dihydropyridine