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Brand: INOmax
Nitric oxide is a colorless gas that is naturally produced in the body and plays a crucial role in various physiological processes. It acts as a signaling molecule, influencing vascular smooth muscle relaxation, neurotransmission, and immune responses. Pharmacologically, nitric oxide can be administered as an inhaled gas to treat pulmonary hypertension in newborns.
Used to treat pulmonary hypertension in newborns and, off-label, for acute respiratory distress syndrome (ARDS).
Outcome:
Increased risk of methemoglobinemia
Mechanism:
Competition for binding sites on hemoglobin
Outcome:
Reduced nitric oxide bioavailability
Mechanism:
Scavenging of nitric oxide
Outcome:
No clinically significant interaction expected
Mechanism:
Different mechanisms of action
Most likely new formulation: controlled-release nitric oxide delivery system (Year: 2026, 60% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of expanded indications for nitric oxide in the next 5 years.
Vasodilator, Inhaled Pulmonary Vasodilator
Nitrogen Oxide