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Generic: Neurokinin Substance C, Neurokinin-C
NSC, or Neurokinin Substance C, is a neuropeptide belonging to the tachykinin family. It acts as a potent vasodilator and plays a crucial role in various physiological processes including pain transmission, inflammation, and regulation of blood pressure. It primarily acts by binding to the NK1 receptor, although it can also interact with NK2 and NK3 receptors to a lesser extent. NSC is involved in both the central and peripheral nervous systems and is associated with conditions such as asthma, migraine, and irritable bowel syndrome.
NSC is involved in the regulation of various physiological processes including pain transmission, inflammation, and regulation of blood pressure.
Outcome:
Synergistic vasodilation and potential hypotension
Mechanism:
Shared receptor activation (NK1)
Outcome:
Increased vasodilation and itching
Mechanism:
Synergistic effects on blood vessels
Outcome:
Minor changes in blood pressure
Mechanism:
Opposing effects on blood vessels
Most likely new formulation: Targeted NK1 receptor agonists with improved pharmacokinetic properties (Year: 2028, 60% confidence)
Based on preclinical studies and ongoing research, there is a moderate (40%) likelihood of NSC-related therapies being approved for specific indications within the next decade.
Neuropeptide, Tachykinin
Peptide