Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Dipentum
Olsalazine is a prodrug of mesalamine, specifically 5-aminosalicylic acid (5-ASA), used to treat ulcerative colitis, a form of inflammatory bowel disease (IBD). It belongs to the aminosalicylate class of drugs and works by delivering 5-ASA to the colon, where it exerts anti-inflammatory effects. It is typically administered orally in capsule form.
For the treatment of ulcerative colitis.
Outcome:
Increased risk of bleeding
Mechanism:
Olsalazine may enhance the anticoagulant effect of warfarin.
Outcome:
Reduced effectiveness of olsalazine
Mechanism:
NSAIDs may exacerbate ulcerative colitis.
Outcome:
Delayed absorption
Mechanism:
Food may slow the absorption of olsalazine.
Most likely new formulation: Controlled-release formulations for improved efficacy and reduced dosing frequency (Year: 2026, 60% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant changes to the regulatory status of olsalazine in the next 5 years.
Aminosalicylate, Anti-inflammatory
Aminosalicylate