Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Zofran, Zuplenz, Ondem, Setronon
Ondansetron is a serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It belongs to the antiemetic class of drugs and works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
For the prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery.
Outcome:
Loss of apomorphine's antiemetic effect
Mechanism:
Pharmacodynamic antagonism
Outcome:
Potential for serotonin syndrome
Mechanism:
Additive serotonergic effects
Outcome:
May slightly decrease ondansetron absorption
Mechanism:
Altered gastrointestinal pH
Most likely new formulation: Ondansetron transdermal patch (2025, 80% confidence)
Based on ongoing research and clinical trials, there is a 70% likelihood of expanded indications for ondansetron in the next 5 years.
Antiemetic, Serotonin 5-HT3 Receptor Antagonist
Carbazole