Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Daypro
Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis, rheumatoid arthritis, and other inflammatory conditions. It works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for producing prostaglandins, substances that mediate pain, inflammation, and fever. Oxaprozin is a long-acting NSAID, meaning it provides extended relief from symptoms.
For the treatment of osteoarthritis, rheumatoid arthritis, and other inflammatory conditions.
Oxaprozin, like other NSAIDs, may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. Oxaprozin may also increase the risk of serious gastrointestinal adverse events, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.
Outcome:
Increased risk of bleeding
Mechanism:
Oxaprozin can displace warfarin from protein binding sites, increasing its free concentration.
Outcome:
Increased risk of gastrointestinal bleeding
Mechanism:
Additive irritant effects on the gastric mucosa.
Outcome:
Reduced oxaprozin absorption
Mechanism:
Antacids can alter gastric pH.
Most likely new formulation: Controlled-release formulation for improved patient compliance (Year: 2025, 70% confidence)
Based on current usage trends and safety profile, there is a low (<5%) likelihood of regulatory changes in the near future.
Nonsteroidal Anti-inflammatory Drug (NSAID)
Propionic Acid Derivative