Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Nembutal, Pentobarbital Sodium
Pentobarbital is a short-acting barbiturate that depresses the central nervous system. It's primarily used as a sedative-hypnotic and anticonvulsant. It enhances the effect of GABA, an inhibitory neurotransmitter, leading to decreased neuronal excitability.
Used for sedation, insomnia, seizures, and as a pre-anesthetic medication.
WARNING: May cause respiratory depression. Can be habit-forming.
Outcome:
Increased sedation, respiratory depression
Mechanism:
Additive CNS depression
Outcome:
Increased sedation
Mechanism:
Additive CNS depression
Outcome:
Reduced sedative effect
Mechanism:
Caffeine antagonism of CNS depression
Most likely new formulation: extended-release for specific indications (Year: 2026, 30% confidence)
Based on decreasing prescription rates, there is a 20% likelihood of increased regulatory scrutiny regarding off-label use within the next 5 years.
Barbiturate, Hypnotic, Sedative, Anticonvulsant
Barbiturate