Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Caverject, Muse, Edex, Prostin VR Pediatric
Alprostadil is a naturally occurring prostaglandin E1 analog used to treat erectile dysfunction, maintain patency of the ductus arteriosus in newborns with congenital heart defects, and promote blood flow in peripheral vascular disease. It acts by relaxing smooth muscle and dilating blood vessels.
Used for erectile dysfunction, maintaining ductus arteriosus patency in newborns, and peripheral vascular disease.
Outcome:
Increased bleeding risk
Mechanism:
Synergistic effects on platelet aggregation
Outcome:
Reduced efficacy of alprostadil
Mechanism:
Inhibition of prostaglandin synthesis
Outcome:
Reduced absorption of alprostadil
Mechanism:
Changes in gastric pH
Most likely new formulation: Topical cream for erectile dysfunction (2025, 80% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of new alprostadil formulations being approved for other indications within the next 5 years.
Prostaglandin, Vasodilator
Prostaglandin E1 analog