Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Bontril, Obezine, Phenzine, Prelu-2, Plegine, Adipost, Anorex-SR, Appecon, Melfiat
Phendimetrazine is a sympathomimetic amine, classified as an anorectic, used as a short-term adjunct in the treatment of exogenous obesity. It stimulates the central nervous system, suppressing appetite and increasing energy expenditure. It is structurally similar to amphetamines and is a Schedule III controlled substance due to its potential for abuse and dependence.
Short-term treatment of exogenous obesity in conjunction with a reduced-calorie diet and exercise.
Outcome:
Hypertensive crisis
Mechanism:
Increased release and decreased metabolism of norepinephrine.
Outcome:
Enhanced pressor effect
Mechanism:
Inhibition of norepinephrine reuptake.
Outcome:
Increased CNS stimulation
Mechanism:
Additive CNS stimulation.
Most likely new formulation: extended-release capsules for improved adherence (Year: 2025, 70% confidence)
Based on current usage trends and emerging alternatives, there is a 15% likelihood of stricter regulatory controls being implemented within the next 5 years.
Anorectic, Sympathomimetic Amine
Morpholine Derivative