Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Neo-Synephrine, Sudafed PE, Little Noses Decongestant, 4-Way Nasal Spray, Vicks Sinex
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine belongs to a class of drugs known as alpha-adrenergic agonists, which work by constricting blood vessels.
For relieving nasal congestion and sinus pressure caused by colds, allergies, and hay fever.
Outcome:
Hypertensive crisis
Mechanism:
Increased norepinephrine levels
Outcome:
Increased side effects
Mechanism:
Additive effects
Outcome:
Decreased antihypertensive effect
Mechanism:
Inhibition of neuronal uptake
Most likely new formulation: sustained-release nasal spray (2025, 70% confidence)
Based on current usage trends and reported adverse events, there is a low ( <5%) likelihood of regulatory changes in the next 2 years.
Decongestant, Alpha-adrenergic agonist
Phenethylamine