Medicines
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Discover all available medicines and treatments
Brand: Noxafil, Posacon
Posaconazole is a triazole antifungal medication used to treat and prevent serious fungal infections, such as invasive aspergillosis, candidiasis, fusariosis, and mucormycosis. It works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. This disruption leads to increased cell membrane permeability and ultimately fungal cell death. It is available in various formulations, including oral suspension, delayed-release tablets, and intravenous injection.
For the treatment and prevention of invasive fungal infections like aspergillosis, candidiasis, fusariosis, and mucormycosis.
Outcome:
Reduced posaconazole levels
Mechanism:
CYP3A4 induction
Outcome:
Reduced posaconazole absorption
Mechanism:
Altered gastric pH
Outcome:
Increased posaconazole absorption
Mechanism:
Enhanced solubility
Most likely new formulation: Extended-release injectable formulation (2026, 80% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of expanded indications for posaconazole in the next 5 years.
Antifungal, Triazole
Triazole