Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Citanest, Oraqix
Prilocaine is a local anesthetic of the amino amide type. It is often used in dentistry and for minor surgical procedures. It works by blocking nerve signals in a specific area of the body, preventing the sensation of pain. Prilocaine has a relatively short duration of action compared to some other local anesthetics.
Prilocaine is used for local anesthesia in dentistry, minor surgical procedures, and pain management.
Outcome:
Increased risk of methemoglobinemia
Mechanism:
Both drugs can induce methemoglobinemia.
Outcome:
Increased prilocaine levels
Mechanism:
Cimetidine inhibits CYP450 enzymes involved in prilocaine metabolism.
Outcome:
No clinically significant interaction
Mechanism:
No known interaction mechanism.
Most likely new formulation: Extended-release prilocaine for postoperative pain management (Year: 2026, 70% confidence)
Based on current usage trends and clinical trial data, there is a low (5%) likelihood of any major regulatory changes for prilocaine in the next 5 years.
Local Anesthetic
Amino Amide